Redx Pharma is a drug discovery and development company formed in 2010. It is focused on improving the characteristics of existing drug classes to create best-in-class new drugs in the areas of cancer, infection and autoimmune disease. The company's work has been endorsed by partnerships with global pharmaceutical companies and the NHS.
Development candidate chosen for leukaemia program
20 October 2016
Redx Pharma Plc is pleased to announce that it has identified a drug development candidate for its reversible Bruton’s Tyrosine Kinase (BTK) inhibitor program. The compound, named RXC005, has the potential to treat the majority of patients suffering from Chronic Lymphocytic Leukaemia (CLL), including those who become resistant to the increasingly used treatment Ibrutinib.
RXC005 is equally potent against the most common type of BTK protein implicated in CLL and the mutant BTK protein, which is currently estimated to be responsible for around 60% of the observed Ibrutinib resistance. Redx’s BTK inhibitor could also offer a reduced side-effect profile compared to Ibrutinib.
Discovering and developing new therapeutics in the area of infectious disease generating a pipeline of novel antibacterial & antiviral drugs.
Modulating the immune system with novel small molecules to treat a range of diseases with high unmet medical need.
Delivering multiple development candidates across a range of mechanistic approaches in cancer treatment.